Clinical Research Paper

A systematic review of randomized controlled trials and network meta-analysis of e-cigarettes for smoking cessation

E-cigarettes, or nicotine vaping products, are potential smoking cessation aids that provide both nicotine and behavioural substitution for combustible cigarette smoking. This review aims to compare the effectiveness of nicotine e-cigarettes for smoking cessation with licensed nicotine replacement therapies (NRT) and nicotine-free based control conditions by using network meta-analysis (NMA).

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Electronic Cigarettes and Oral Health

Electronic Cigarettes and Oral Health

Novel nicotine products, particularly electronic cigarettes (e-cigarettes), have become increasingly popular over the past decade. E-cigarettes are sometimes regarded as a less harmful alternative to tobacco smoking, and there is some evidence of their potential role as a smoking cessation aid. However, there are concerns about their health consequences, particularly in users who are not tobacco smokers, and also when used long term. Given the mode of delivery of these products, there is potential for oral health consequences.

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E-cigarettes and nicotine abstinence: a meta-analysis of randomised controlled trials

E-cigarettes and nicotine abstinence: a meta-analysis of randomised controlled trials

Objectives: To determine the effects of electronic cigarettes (e-cigarettes) as a therapeutic intervention compared to nicotine replacement therapy (NRT) on nicotine abstinence.
Methods: Two authors independently searched the PubMed, Embase, PsycInfo and Cochrane Central Register of Controlled Trials databases for articles published up to and including 10 July 2021. We included randomised controlled trials (RCTs) in which nicotine e-cigarettes were compared to NRT among current cigarette users.

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Effect of Electronic Cigarettes on Smoking Reduction and Cessation in Korean Male Smokers: A Randomized Controlled Study

Effect of Electronic Cigarettes on Smoking Reduction and Cessation in Korean Male Smokers: A Randomized Controlled Study

Introduction: New approaches to electronic cigarettes (e-cigarettes) as a form of nicotine replacement therapy (NRT) may reduce the rates of tobacco-related disease and mortality. Therefore, we investigated the effect of e-cigarettes on smoking cessation compared with nicotine gum.

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Randomized Trials of e-Cigarettes for Smoking Cessation

Few topics in public health and medicine are as contentious as electronic cigarettes (e-cigarettes), a diverse and rapidly evolving array of products that appeared on the consumer market a decade ago. e-Cigarettes are battery-powered devices that heat a solution, typically containing nicotine and other chemicals including flavorings, to produce an aerosol that users inhale or "vape." e-Cigarettes do not burn tobacco to generate smoke, and it is the many chemicals in tobacco smoke-not the nicotine-that are responsible for the global burden of tobacco-related disease that accounts for an estimated 6 million deaths worldwide and nearly half a million deaths in the US each year

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Randomized Trial of E-Cigarettes vs Nicotine Replacement Therapy - E-Cigarettes vs Nicotine Replacement Therapy

This trial demonstrated that e-cigarettes are more efficacious compared with nicotine-replacement products for abstinence at 1 year among participants motivated to quit smoking, although the overall success rate remains very low. The goal of the trial was to assess the efficacy of refillable e-cigarettes as compared with nicotine replacement among adults seeking help to quit smoking.

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QuitNic: A Pilot Randomized Controlled Trial Comparing Nicotine Vaping Products With Nicotine Replacement Therapy for Smoking Cessation Following Residential Detoxification

QuitNic: A Pilot Randomized Controlled Trial Comparing Nicotine Vaping Products With Nicotine Replacement Therapy for Smoking Cessation Following Residential Detoxification

The QuitNic pilot trial aimed to test the feasibility of providing a nicotine vaping product (NVP) compared with combination nicotine replacement therapy (NRT) to smokers upon discharge from a smoke-free residential substance use disorder (SUD) treatment service.

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A Randomized Controlled Trial Evaluating the Efficacy of E-Cigarette Use for Smoking Cessation in the General Population: E3 Trial Design

A Randomized Controlled Trial Evaluating the Efficacy of E-Cigarette Use for Smoking Cessation in the General Population: E3 Trial Design

Background: Smoking cessation improves morbidity and mortality among smokers who achieve long-term abstinence. Many smokers are using electronic cigarettes (e-cigarettes) to attempt to quit, despite a lack of data concerning their efficacy and safety for smoking cessation.

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