Nicotine Administration Augments Abdominal Aortic Aneurysm Progression in Rats
Inflammation and elastin degradation are key hallmarks in the pathogenesis of abdominal aortic aneurysms (AAAs). It has been acknowledged that activation of alpha7 nicotinic acetylcholine receptors attenuates inflammation, termed the cholinergic anti-inflammatory pathway (CAP).
Long-term e-cigarette aerosol exposure causes pulmonary emphysema in adult female and male mice
This study aimed to evaluate long-term exposure to conventional cigarette smoke (CC) and electronic cigarette (EC) aerosol in adult male and female C57BL/6 mice. Forty-eight C57BL/6 mice were used, male (n = 24) and female (n = 24), both were divided into three groups: control, CC and EC. The CC and EC groups were exposed to cigarette smoke or electronic cigarette aerosol, respectively, 3 times a day for 60 consecutive days.
Prolonged nicotine exposure reduces aversion to the drug in mice by altering nicotinic transmission in the interpeduncular nucleus
Nicotine intake is likely to result from a balance between the rewarding and aversive properties of the drug, yet the individual differences in neural activity that control aversion to nicotine and their adaptation during the addiction process remain largely unknown.
The relative reinforcing efficacy of nicotine in an adolescent rat model of attention-deficit hyperactivity disorder
Introduction: Attention-deficit/hyperactivity disorder (ADHD) is an independent risk factor for tobacco use disorder. Individuals with ADHD are more likely to begin smoking at a younger age, become a daily smoker sooner, smoke more cigarettes per day, and exhibit greater nicotine dependence than individuals without ADHD.
The risk profile of electronic nicotine delivery systems, compared to traditional cigarettes, on oral disease: a review
The use of electronic nicotine delivery systems (ENDS) has exploded, especially among teenagers and new smokers, amid widespread awareness of the dangers of traditional tobacco and restrictions on smoking. However, the risk effects of ENDS on physical health, especially oral health, are still ambiguous. The purpose of this study was to review the available evidence on risks of ENDS on oral health, and compares the differences between ENDS and traditional cigarettes.
Disposable e-cigarettes and cigarette butts alter the physiology of an aquatic plant Lemna minor (Lemnaceae)
Cigarette butts are one of the most littered single-use plastic items worldwide and can have ecotoxicological effects. e-Cigarettes (or 'vapes') have gained popularity globally as an alternative to tobacco-based cigarettes in recent years. The increased availability of disposable e-cigarettes has resulted in a rise in their littering, presenting a complex form of e-waste in the environment, yet the environmental impacts of littered e-cigarettes are largely unknown.
The effects of dual IQOS and cigarette smoke exposure on airway epithelial cells: implications for lung health and respiratory disease pathogenesis
Background: Cigarette smoking remains a primary cause of chronic lung diseases. After a steady decline, smoking rates have recently increased especially with the introduction of newer electronic nicotine delivery devices, and it is also emerging that dual- or poly-product usage is on the rise.
Acute health effects of heated tobacco products: comparative analysis with traditional cigarettes and electronic cigarettes in young adults
Background: Heated tobacco products (HTPs) were designed to deliver nicotine by heating the tobacco instead of burning it. This study aimed to examine the acute health effects on the respiratory and cardiovascular systems during the use of HTPs and compare these effects with acute health effects evoked by cigarette smoking or electronic cigarettes (e-cigarettes).
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