THR PubMed Research

Comprehensive review of the national surveys that assess E-cigarette use domains among youth and adults in the United States

Surveillance of e-cigarette use among different population groups is important for the timely implementation and evaluation of tobacco regulatory policies.

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Effect of the nicotine replacement therapy on biomarkers of inflammation, endothelial dysfunction, oxidative stress and lipids in smokers who quit smoking

Our previous study showed major changes in biomarkers on quitting compared to the smoking state. They reflected a decrease of inflammation, endothelial activation, and oxidative stress, as well as an improved lipid profile.

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Effects of heated tobacco product aerosol extracts on DNA methylation and gene transcription in lung epithelial cells

Smoking causes DNA methylation (DNAm) alterations that lead to lung cancer development. Although the use of heated tobacco products (HTPs) has recently increased, their impact on health remains unclear. This study aimed to evaluate the effects of HTPs on DNAm and gene transcription in human lung epithelial cells in vitro.

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Dopamine D1-like receptor activation decreases nicotine intake in rats with short or long access to nicotine

The use of nicotine and tobacco products is highly addictive. The dopaminergic system plays a key role in the initiation and maintenance of nicotine intake.

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Subregion specific neuroadaptations in the female rat striatum during acute and protracted withdrawal from nicotine

Epidemiological studies and clinical observations suggest that nicotine, a major contributor of the global burden of disease, acts in a partially sex specific manner. Still, preclinical research has primarily been conducted in males. More research is thus required to define the effects displayed by nicotine on the female brain.

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A Cytological Study of Oral Human Papillomavirus (HPV) Infection Among Electronic Cigarette Smokers in Al-Madinah Al-Munawara

Objective This study aims to determine how electronic cigarette (e-cigarette) use contributes to the spread of the human papillomavirus (HPV) and to assess the potential cellular proliferative activity it may produce. Methodology In Madinah, a case-control study was conducted between October 2022 and March 2023.

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Prevalence of use, perceptions of harm and addictiveness, and dependence of electronic cigarettes among adults in Kuwait: A cross-sectional study

Electronic cigarettes (e-cigarettes) have become one of the most common forms of nicotine delivery used by youth and young adults worldwide. Given the lack of epidemiologic data in Kuwait, this study sought to estimate the prevalence of e-cigarette use, assess perceptions of harm and addictiveness of e-cigarettes, measure the level of dependence on e-cigarettes and assess factors associated with dependence level among adults.

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