LMIC News

AMPK-mediated autophagy is involved in the protective effect of canagliflozin in the vitamin D3 plus nicotine calcification model in rats

Vascular calcification (VC) is a major risk factor for cardiovascular events. A mutual interplay between inflammation, oxidative stress, apoptosis, and autophagy is implicated in its development. Herein, we aimed to evaluate the potential protective effects of canagliflozin in a vitamin D3 plus nicotine (VDN) model of VC, and to explore potential mechanisms.

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The toxic effects of electronic cigarette aerosol and cigarette smoke on cardiovascular, gastrointestinal and renal systems in mice

Electronic cigarette (EC) has been suggested to be less harmful than cigarette smoking, but the research on the full extent of their harm reduction potential is still lacking.

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The volatile release evaluation of nicotine from snus products under different storage conditions based on surface-enhanced Raman spectroscopy technology

Surface enhanced Raman spectroscopy (SERS) is a highly sensitive analytical detection technique that provides unique chemical and structural information on target molecules. Snus is a type of tobacco product that can release nicotine and other components under certain humidity and temperature without burning, and the evaluation of its nicotine release under different storage conditions is very important for understanding its characteristics, regulating its components, and setting reasonable storage conditions.

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A comparative study of the effects of electronic cigarette and traditional cigarette on the pulmonary functions of C57BL/6 male mice

Electronic cigarettes (E-cigs) are in a controversial state. Although E-cig aerosol generally contains fewer harmful substances than smoke from burned traditional cigarettes, aerosol along with other compounds of the E-cigs may also affect the lung functions and promote the development of lung-related diseases.

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Effect of green tea and nicotine on haematological and biochemical parameters and histopathology of bone marrow and spleen on albino rats

We investigate the effects of green tea extract (GTE) on the attenuation of nicotine hematotoxicity, oxidative stress, inflammation and spleen and bone marrow structural lesions. Rats were treated by injecting nicotine (1,5mg/kg b.w. for 7 weeks) intraperitoneally and thereby supplementing GTE 2% orally to them.

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GFN Voices with Michael Kariuki

GFN Voices with Michael Kariuki

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Tobacco alternatives: Educating youth on vaping dangers better than banning it

LAST month, the government sent the Tobacco Product and Smoking Control Bill back to the Parliamentary Special Select Committee for further review.

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High mortality rates prompt experts to renew calls to curb smoking across Kingdom

AMMAN - Despite official calls to combat and reduce smoking, smoking-related deaths in Jordan are estimated around 8,000 annually with high rates of cancer and hundreds of cases of chronic disease, according to experts.

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